Path of Exile 2: Best Uniques to Chance and How to Use Orbs of Chance Efficiently

In Path of Exile 2, Unique items are among the most coveted treasures you can find. Each Unique comes with Path of Exile 2 Currency predetermined modifiers that make it distinct from other items in the same category - sometimes turning an ordinary weapon or armor piece into the cornerstone of an entire build. Whether you're crafting the ultimate boss killer or a farming powerhouse, Uniques often define how your character plays.

Currently, there are over 350 Unique items in Path of Exile 2, and farming them all is no easy task. Drops are completely random, meaning you can grind for hours without seeing the item you want. However, one method stands above traditional farming - "Chancing" your Uniques using the Orb of Chance. This simple yet risky crafting mechanic lets you transform ordinary items into potential Uniques of the same base type.

In this guide, we'll go over the best Uniques to Chance, explain how Orbs of Chance work, and share practical tips to increase your odds of success when hunting for endgame-defining items.

What Makes Uniques in Path of Exile 2 So Valuable

Unlike rare or crafted gear, Unique Path of Exile 2 Items feature fixed modifiers that can't be altered. Every drop of the same Unique item carries the same modifiers, with only minor numerical variation. Some Uniques are so powerful they completely reshape entire builds - increasing damage multipliers, modifying skill interactions, or unlocking entirely new playstyles.

Because of their build-defining potential, the right Unique can often be worth thousands of Chaos Orbs in trade leagues - which is why learning to target them through Chancing can save you both time and currency.

The Orb of Chance is a crafting currency that gives a normal (white) item a chance to upgrade into a Magic, Rare, or Unique item. When you use it on a base type that has a Unique version, it can transform into that Unique, though the odds are incredibly low.

Here's how it works:

The base item type matters. For example, using an Orb of Chance on a Viper Cap has a chance (however small) to become Constricting Command, since they share the same base.
You can only change white items (non-magic, non-rare).
You cannot change corrupted or mirrored items.
There is no guaranteed success rate, but it's widely believed to be under 1% for Uniques.

This system allows players to buy POE2 Currency in bulk, stockpile Orbs of Chance, and mass-Chance target bases in high-density maps for efficient farming.

Tips for Efficient Chancing

Farm the correct base type: Always make sure the item base you're using can actually result in your target Unique.
Use item filters: Highlight desirable bases for easier farming.
Bulk Chance in batches: The more attempts, the better your odds.
Don't chance valuable bases you can sell: If the base itself is expensive, it may be better to trade it.
Remember: luck is streaky. You might use 50 Orbs of Chance without success - or you might hit gold on your first try.

Final Thoughts

Chancing Uniques in Path of Exile 2 is equal parts strategy and gamble. While the odds may not always be in your favor, targeting the right bases and focusing on build-defining Uniques like Headhunter, Atziri's Acuity, or Astramentis can make the grind worthwhile.

With over 350 Uniques in the game and more being added regularly, mastering Orb of Chance farming will remain one of cheap POE 2 Orbs the most rewarding pursuits for players looking to build, trade, and dominate the endgame in Path of Exile 2.